Progesterone in IVF: the key facts patients need to know

If you’re having a fresh IVF cycle, donor-egg treatment, embryo adoption or a frozen embryo transfer (FET), progesterone is one of the most important medications you’ll take. It helps prepare your endometrium for for implantation and supports the early weeks of pregnancy – before the placenta fully takes over your hormonal support.

The right progesterone support can make a real difference to treatment outcomes, but the format and dose aren’t the same for everyone. Recent research from ESHRE sets out the progesterone options available. Vaginal progesterone application is the gold standard, since it’s easy to do, less painful than injections, and absorbed well in most cases.

Why progesterone matters so much in IVF

In a natural cycle, the follicle that released the egg becomes the corpus luteum. This produces progesterone, which makes the womb lining super-receptive for an incoming embryo.

But IVF adjusts this hormonal activity. Ovarian stimulation, egg collection, and the medication used to control ovulation, can all disrupt the body’s natural luteal phase. So the body can’t be relied on to produce enough progesterone during fertility cycles – notably in fresh IVF (or donor-egg) cycles and medicated FETs. Even natural-cycle FETs can benefit from some man-made progesterone.    

Without adequate progesterone during a fertility-treatment cycle, the endometrium may not be in-sync with the embryo. This can seriously reduce the chance of implantation and ongoing pregnancy, regardless of which progesterone format is used.       

Fresh IVF, donor eggs and FETs: is progesterone in IVF always needed?

In fresh IVF cycles, progesterone support is standard because, as discussed, stimulating medication (usually injections like Menopur or Gonal-f) can disturb the luteal phase. Current practice is to start it on the day of egg retrieval (or soon after), or five days before an embryo transfer using a blastocyst.

In donor-egg cycles, progesterone is essential because the recipient’s ovaries are usually down-regulated (turned off). So they don’t ‘speak’ to the womb lining – at least not by the time of transfer. So synthetic progesterone becomes a key part of making the endometrium receptive. Alongside estrogen support, donor-egg patients mustn’t miss a dose.        

The same rules apply to medicated FETs: progesterone is vital in the early stages because the lining is being prepared artificially. The estrogen has a down-regulating effect. Natural ovulation doesn’t happen which would normally give the green light to the hormone. When it comes to FETs and donor-treatment cycles, there’s no green light.   

In natural-cycle FETs, the picture is greyer. Some patients do produce their own progesterone after ovulation, but evidence suggests that some progesterone supplementation leads to higher live birth and clinical pregnancy rates in this type of cycle. Most women still choose medicated cycles over natural ones.     

The four progesterone formats

There are four main progesterone routes for fertility cycles: vaginal, intramuscular, subcutaneous and oral. Each format has its pros and cons.

Vaginal progesterone

This is the most common progesterone format used in fertility treatment. It’s usually prescribed as pessaries (Cyclogest), capsules (Utrogestan) or gel (Crinone). Vaginal progesterone gets the hormone close to the uterus. So unlike oral pills, which are rarely used, it doesn’t need to be processed by the liver. It’s often seen as the most effective form of progesterone.    

Patients sometimes notice discharge or messiness. Vaginal products can also cause irritation, and if that’s hard to tolerate clinics may suggest rectal application of Cyclogest instead. Leakage may cause patients to worry that the medication isn’t ‘staying in’. But, in most cases, a sufficient amount is still absorbed.   

Vaginal progesterone remains the standard, evidence-based option. Most clinics use it for routine luteal support. It’s also a cheaper and more user-friendly option than injections (see below). But watch out for vaginal oil capsules – these may improve live birth rates and reduce the miscarriage risk for certain patients.            

Intramuscular progesterone

Intramuscular progesterone is usually applied daily into the buttock. These progesterone-in-oil (PIO) injections work well because absorption is reliable and steady. (Our clinic uses Agolutin.) A good number of fertility doctors like PIO injections, especially in cycles where they want super-reliable progesterone levels. They may even be the most effective format for FET cycles.   

The trade-off is application. Intramuscular injections can be painful. They are also awkward to self-administer, so a partner or healthcare professional may need to do them. But despite the inconvenience, the once-a-day simplicity can trump the hassle of twice-daily vaginal medication.

Subcutaneous progesterone

Subcutaneous progesterone injections (Lubion, Prolutex) are usually applied into the fatty tissue of the lower abdomen, like the standard FSH injections IVF patients know well – and there’re an antidote to the more unwieldy PIO injections. But convenience comes at a cost – they’re probably the most expensive form of progesterone.

But their effectiveness is excellent. They’re particularly good at accelerating progesterone levels when a blood check reveals a poor score, perhaps around embryo transfer time. Combining them with vaginal progesterone also be ensure levels are adequate for fertility patients.  

Oral progesterone

Oral progesterone (Utrogestan) is generally less well regarded for IVF luteal support. It can cause quite pronounced side effects, like sleepiness, dizziness and nausea, and it’s often sidelined by clinics.    

What doses of progesterone do fertility patients take?     

Every patient’s protocol is different, but typical doses in fresh and frozen fertility cycles, as advised by ESHRE, are:

  • 50 mg once daily for intramuscular progesterone
  • 25 mg once daily for subcutaneous progesterone
  • 90 mg once daily for vaginal progesterone gel
  • 200 mg three times daily for micronized vaginal capsules
  • 400 mg twice daily for vaginal pessaries

Timing matters

Progesterone support in fertility cycles during isn’t just about brand and dose. Timing is crucial. For fresh IVF cycles, as discussed, starting progesterone on egg retrieval day (or a day or two later – ask your clinic) is the norm.    

For frozen cycles, knowing the age of the embryo when it was frozen is crucial. Progesterone is typically started five days before a blastocyst transfer. But if you froze a cleavage-stage (day 3) embryo, it’s usually added in three days before transfer. Double check with your clinic.

Then there’s your endometrial receptivity. If you’ve had the ERA test, the report will pinpoint the start date and time of your first progesterone application, as well as the best window for implantation. One of our patients had to start their progesterone four days before transfer. Another started it six days earlier. Variations exist.    

If you’re taking twice-daily progesterone, try to space the doses exactly 12 hours apart. If it’s once a day, stick to the same time each day. Most importantly, don’t miss a single dose.          

How long do you stay on progesterone?

Most, if not all, clinics will advise staying on progesterone until your pregnancy test. Then, if the result is positive, for several more weeks.

After that positive result, clinic practice varies. Many clinics continue until around 8 to 10 weeks of pregnancy, when placental hormone production is established. Your own clinic’s plan should always take priority: the right end date depends on your treatment type and your medical history.

Some patients may be asked to continue their progesterone until their second or third trimester. But most stop earlier, and the usual advice is to wean off your IVF meds gently. This often means halving your daily dose a week before you stop altogether.        

Practical advice for patients taking progesterone

Organisation is key. Here are some simple steps to make your progesterone regime less stressful:

  • Take every dose exactly as prescribed. Consistency matters.
  • Set alarms or alerts so you don’t miss a dose.
  • Ask you clinic what to do if you’re late – in advance
  • Don’t panic if you experience discharge while on vaginal progesterone: you’re probably absorbing enough.
  • Rotate injection sites if you use injections.
  • Tell your clinic about side effects, bleeding or difficulty coping with application.

Most importantly, don’t compare your protocol too closely with someone else’s. IVF forums can be helpful but also misleading. Different progesterone plans can all work, but only your clinic can advise you on your own treatment.   

Progesterone and IVF – the bottom line

Progesterone plays a core role in supporting implantation and early pregnancy. The best form and dose depend on the type of fertility treatment you have, your protocol, and your clinic’s approach.

For most patients, vaginal progesterone works fine. For a minority, intramuscular or subcutaneous progesterone offers more reliable support. The clear message from the current evidence is that there’s no clear progesterone ‘winner’. A well-timed, individualised progesterone strategy will give you the best chance of success – and that comes from your clinic.

FAQs

Progesterone helps prepare and stabilise the womb lining so an embryo can implant and keep developing. IVF medications can disrupt the body’s natural luteal phase, so extra support is often needed to replace what the ovaries may not produce reliably.

Usually, yes. It’s essential in medicated FET cycles. and may also improve outcomes in natural-cycle FETs for some patients. Recent evidence suggests progesterone support in natural FETs can increase clinical pregnancy and live birth rates.

Neither is automatically best for everyone. Vaginal progesterone is common and convenient for many patients, while injections may give more predictable absorption in some cases. Combining both formats may be a good option in some cases.

Yes. If progesterone is too low, your endometrial lining may not be optimally receptive when your embryo is transferred. This seem to be especially relevant in medicated FET cycles, where some clinics now monitor progesterone levels and adjust brand or dosage if needed.

Contact your clinic as soon as possible for advice. Don’t guess, double up or stop on your own unless they tell you to. Timing matters with progesterone, and your clinic will advise the safest way to get back on track.

They can be. Common side effects include bloating, tiredness, breast tenderness, discharge, soreness at injection sites and mood changes. Some symptoms overlap with early pregnancy, which can make the two-week wait feel especially confusing.

Many clinics continue progesterone until the pregnancy test and, if positive, for several more weeks after that. A common stop point is around 8 to 10 weeks of pregnancy, but your own clinic’s instructions should always come first.

Usually, no. With vaginally-applied progesterone, discharge is very common and often reflects the medication base rather than poor absorption. It can be messy and annoying, but it doesn’t usually mean the progesterone isn’t working properly.

Oral progesterone is not usually the first choice in fertility-treatment cycles because it can cause side effects like dizziness and nausea. Most clinics prefer vaginal, intramuscular or subcutaneous progesterone.

No. Progesterone is essential support, but it can’t overcome every other factor that affects IVF success, such as embryo quality, endometrial timing and underlying fertility issues. It improves the conditions for pregnancy, but it’s not a guarantee on its own.

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 Last updated: 16 August 2026 at 6:59 pm

96 Responses

  1. great site. easy to read.
    One thing … you mention PROLUTEX subcutaneous progesterone . it’s not called that in UK .
    in the UK it is called LUBION

  2. great site. easy to read.
    One thing … you mention PROLUTEX subcutaneous progesterone . it’s not called that in UK .
    in the UK it is called LUBION

  3. Hi. Thanks for the info. Due to a mix-up at my clinic, I have been using a 1/2″ needle for my PIO injections from 5 days prior to FET (suppression cycle) until the mistake was realized and corrected 3.5 days after FET. Will any of that PIO have made it to where it needs to be, or did I just blow my one and only chance at pregnancy? I am a thin and muscular person, if that helps. Thanks.

  4. Hi. Thanks for the info. Due to a mix-up at my clinic, I have been using a 1/2″ needle for my PIO injections from 5 days prior to FET (suppression cycle) until the mistake was realized and corrected 3.5 days after FET. Will any of that PIO have made it to where it needs to be, or did I just blow my one and only chance at pregnancy? I am a thin and muscular person, if that helps. Thanks.

  5. Has anybody used prontogest and crinone at the same time? I had two previous transfers and used only prontogest (one injection per day). Both pregnancies ended in a miscarriage. I’ve now had another transfer and I’ve been checking my beta hcg since day 10 of the transfer and it is doubling as required. I had some cramping and some spotting about 5 days before my scheduled period (which is due on 14.10). I’m very anxious that not having enough progesterone in my body, I may start the period and the pregnancy will be expelled. I asked my doctor if I could add crinone in addition to prontogest but had no definitive answer… I was told that additional dosage of progesterone will not harm the baby. I am very keen to do everything to stop the uterus contractions so that a healthy pregnancy proceeds.

  6. Has anybody used prontogest and crinone at the same time? I had two previous transfers and used only prontogest (one injection per day). Both pregnancies ended in a miscarriage. I’ve now had another transfer and I’ve been checking my beta hcg since day 10 of the transfer and it is doubling as required. I had some cramping and some spotting about 5 days before my scheduled period (which is due on 14.10). I’m very anxious that not having enough progesterone in my body, I may start the period and the pregnancy will be expelled. I asked my doctor if I could add crinone in addition to prontogest but had no definitive answer… I was told that additional dosage of progesterone will not harm the baby. I am very keen to do everything to stop the uterus contractions so that a healthy pregnancy proceeds.

  7. Can pessaries hurt the baby if you do 2 at once as my Dr told me to use 2 at night and iv just found out the should not be taken that way please tell me have I hurt my baby

  8. Can pessaries hurt the baby if you do 2 at once as my Dr told me to use 2 at night and iv just found out the should not be taken that way please tell me have I hurt my baby

  9. I’ll be going for ET in a week’s time. My hospital normally administers cyclogest few days before ET and continues after the transfer. My last procedure failed.Having heard so much about progesterone injections, am considering giving it a try. My question now is this: Has anyone started with cyclogest and later switched over to progesterone injection or can one do the two at the same time just to maximize success.

  10. I’ll be going for ET in a week’s time. My hospital normally administers cyclogest few days before ET and continues after the transfer. My last procedure failed.Having heard so much about progesterone injections, am considering giving it a try. My question now is this: Has anyone started with cyclogest and later switched over to progesterone injection or can one do the two at the same time just to maximize success.

  11. I have a question. I am first time ivf.one egg. It was the 13th day post transfer when i saw blood when cleaning myself on the toilet. I have had brownish discarg for 2 days.each day a bit more. In the afternoon after estima i got brownish spotting again. I am very confused cause its changing from blood to brown. Do you think that my body is lacking of progesterone? I am taking pills into vagina. When i lay down its mostly brown but when i move around i het blood.or its my period and the progesterone is stopping the period to come? Is that possible? My periods or heavy? Changing every hour ussualy,my pads.today is the 14th day and i have blèed a bit but its far from what i would call my period.i jad one pad the whole day.after taking the second progesterone there was brown discarge instead of blood. And when i put in the last pill for today in the vagina my finger was clear.no blood on it like in the morning.i have my blood test tomorrow and i doubt i will get any explenaction from my hospital.i am just a number there.

  12. I have a question. I am first time ivf.one egg. It was the 13th day post transfer when i saw blood when cleaning myself on the toilet. I have had brownish discarg for 2 days.each day a bit more. In the afternoon after estima i got brownish spotting again. I am very confused cause its changing from blood to brown. Do you think that my body is lacking of progesterone? I am taking pills into vagina. When i lay down its mostly brown but when i move around i het blood.or its my period and the progesterone is stopping the period to come? Is that possible? My periods or heavy? Changing every hour ussualy,my pads.today is the 14th day and i have blèed a bit but its far from what i would call my period.i jad one pad the whole day.after taking the second progesterone there was brown discarge instead of blood. And when i put in the last pill for today in the vagina my finger was clear.no blood on it like in the morning.i have my blood test tomorrow and i doubt i will get any explenaction from my hospital.i am just a number there.

  13. Hi all, am using utrogestan 200 gel (3 times a day) in the vigina . Am on my 6th day since embroyo tranfer, i see no sign of discharge but my gel comes out quet often?
    Should i be worried

  14. Hi all, am using utrogestan 200 gel (3 times a day) in the vigina . Am on my 6th day since embroyo tranfer, i see no sign of discharge but my gel comes out quet often?
    Should i be worried

  15. I was supposed to take Utrogestan at 8am and 8pm.. i forgot the night dose and took it an hour late i.e. at 9pm. Will this impact the outcome. This is day 11 post FET

  16. I was supposed to take Utrogestan at 8am and 8pm.. i forgot the night dose and took it an hour late i.e. at 9pm. Will this impact the outcome. This is day 11 post FET

  17. Thanks for the information. I’m doing IVF -(PGD), and the transfer of the frozen embryos is in three days- Tuesday. I was supposed to start utrogestan one day ago- Friday and I completely forgot. I started today, and I’m taking two in the morning and two at night. Do you think that’s going to ruin my chances of getting pregnant?

  18. Thanks for the information. I’m doing IVF -(PGD), and the transfer of the frozen embryos is in three days- Tuesday. I was supposed to start utrogestan one day ago- Friday and I completely forgot. I started today, and I’m taking two in the morning and two at night. Do you think that’s going to ruin my chances of getting pregnant?

  19. I have done IVF 14 days ago I have done blood test HCG results 35, and from 1st day after the IVF Dr asked me to take below medication on daily basis isn’t too much medication can you tell me that if its okay if i can take it?
    – folic acid 5mg tablet one daily
    – vitamin B6 tablet one daily
    – Cyclogest Suppositories 400 mg vaginal use twice daily
    – Estrofem tablet 2mg twice daily
    – Prednisolone tablets 5 mg 2 tablet twice daily
    – Clexane 4000 injection daily under the skin in the stomach one daily
    – Duphaston 10 mg tablets 3 times daily
    – B12 on daily basis 400iu

  20. I have done IVF 14 days ago I have done blood test HCG results 35, and from 1st day after the IVF Dr asked me to take below medication on daily basis isn’t too much medication can you tell me that if its okay if i can take it?
    – folic acid 5mg tablet one daily
    – vitamin B6 tablet one daily
    – Cyclogest Suppositories 400 mg vaginal use twice daily
    – Estrofem tablet 2mg twice daily
    – Prednisolone tablets 5 mg 2 tablet twice daily
    – Clexane 4000 injection daily under the skin in the stomach one daily
    – Duphaston 10 mg tablets 3 times daily
    – B12 on daily basis 400iu

  21. Hello ladies! After 3 embryo transfer I’m on 600mg Utrogestan per day, orally, and a 25mg shot of Prolutex in the morning. (I’m almost 42 years old, and this is our 2nd ivf attempt with my own eggs.) Sometimes I get dizzy for half and hour or so after having taken orally a 200mg pill of Utrogestan, sometimes not. But what worries me is that Prolutex gives me a rash in the chest area. I spoke to my doctor about it and he said that it can’t be from Prolutex, well, I know my body better than that, no allergies so far by any reason, and it can’t be a coincidence that the day I started Prolutext the rash appeared, in both ivf cycles. Anyone with the same reaction?
    I was aslo prescribed Salospir, but after reminding my doctor about my ulcerative colitis case he decided that it’s not necessary to take it or any other drug instead of it. I asked about flaxseed oil, he said no. Any thoughts about that?
    Good luck to everyone!!!

    1. Hey, I’m on 600mg utrogestan vaginally (6dp5dt of our first Donor egg/sperm cycle) and also have a rash on my chest and arm. We had our treatment in Spain and just assumed the rash was prickly heat, but it hasn’t gone away. Could be the utrogestan causing it for us both?!

  22. Hello ladies! After 3 embryo transfer I’m on 600mg Utrogestan per day, orally, and a 25mg shot of Prolutex in the morning. (I’m almost 42 years old, and this is our 2nd ivf attempt with my own eggs.) Sometimes I get dizzy for half and hour or so after having taken orally a 200mg pill of Utrogestan, sometimes not. But what worries me is that Prolutex gives me a rash in the chest area. I spoke to my doctor about it and he said that it can’t be from Prolutex, well, I know my body better than that, no allergies so far by any reason, and it can’t be a coincidence that the day I started Prolutext the rash appeared, in both ivf cycles. Anyone with the same reaction?
    I was aslo prescribed Salospir, but after reminding my doctor about my ulcerative colitis case he decided that it’s not necessary to take it or any other drug instead of it. I asked about flaxseed oil, he said no. Any thoughts about that?
    Good luck to everyone!!!

    1. Hey, I’m on 600mg utrogestan vaginally (6dp5dt of our first Donor egg/sperm cycle) and also have a rash on my chest and arm. We had our treatment in Spain and just assumed the rash was prickly heat, but it hasn’t gone away. Could be the utrogestan causing it for us both?!

  23. Hi I had my frozen embryo transfer on the 2nd
    June. I done a home pregnancy test this afternoon and it was negative, I’m devastated.
    Is it possible that it could be wrong as I was impatient and tested two days early!

    This is our 3rd round, first we miscarriaged and second it did not catch. We have put two in this time.

    Feeling so heartbroken right now with life.

  24. Hi I had my frozen embryo transfer on the 2nd
    June. I done a home pregnancy test this afternoon and it was negative, I’m devastated.
    Is it possible that it could be wrong as I was impatient and tested two days early!

    This is our 3rd round, first we miscarriaged and second it did not catch. We have put two in this time.

    Feeling so heartbroken right now with life.

  25. Hi I’ve done my fet done October 5 but the thing is only stuffy nose is very annoying while I’m sleeping at night and aside from that nothing my test is on 16th of October I’m wondering is anyone got the same condition? Thanks

  26. Hi I’ve done my fet done October 5 but the thing is only stuffy nose is very annoying while I’m sleeping at night and aside from that nothing my test is on 16th of October I’m wondering is anyone got the same condition? Thanks

  27. What should be the right progesterone supplementation in IVF OD pregnancy,particularly in 1st 2nd & 3rd trimesters of pregnancy,please guide?

  28. What should be the right progesterone supplementation in IVF OD pregnancy,particularly in 1st 2nd & 3rd trimesters of pregnancy,please guide?

  29. Hi, I have my transfer tomorrow morning at 8:30am. Do I take my pessary in the morning before the transfer and if so at what time?
    Thank you

  30. Hi, I have my transfer tomorrow morning at 8:30am. Do I take my pessary in the morning before the transfer and if so at what time?
    Thank you

  31. What number to RE’s like to see when doing progesterone shots and taken vaginally ? 3 days before beta my wife’s at 20. 28 . Is this good or at a exceptable level? Thanks for any help

  32. What number to RE’s like to see when doing progesterone shots and taken vaginally ? 3 days before beta my wife’s at 20. 28 . Is this good or at a exceptable level? Thanks for any help

  33. Hii, i have gone through my FET i have been taking endometrin 100 mg 4 times a day and prontogest inject once a day, 2 days before doc did my test progestrone and E2 level that came p-20 E2-212 , should it be good level for pregnancy? Am i pregnant could you tell me about it what should be the level?

  34. Hii, i have gone through my FET i have been taking endometrin 100 mg 4 times a day and prontogest inject once a day, 2 days before doc did my test progestrone and E2 level that came p-20 E2-212 , should it be good level for pregnancy? Am i pregnant could you tell me about it what should be the level?

  35. Hi
    I have a question, this is my first ivf and I did my transfer on the first of April, after 14days I went for my first appointment which was positive and I was told to come in two weeks time for first scan and when the scan was carried out they found out that the embryo is not found in the sac, pls what could be the reason or is it something to worry about. Thanks

  36. Hi
    I have a question, this is my first ivf and I did my transfer on the first of April, after 14days I went for my first appointment which was positive and I was told to come in two weeks time for first scan and when the scan was carried out they found out that the embryo is not found in the sac, pls what could be the reason or is it something to worry about. Thanks

  37. hey A.A
    I have taken iui treatment this month on 13,14 Nov 2019. today i forgot taking cyclogest in morning
    now i took it but i suppose to take 2nd dose in midnight
    does it work?

  38. hey A.A
    I have taken iui treatment this month on 13,14 Nov 2019. today i forgot taking cyclogest in morning
    now i took it but i suppose to take 2nd dose in midnight
    does it work?

  39. I took a test 9 days after 5 day transfer the test was negative but I am 7 days late on my period is there any chance I could still be pregnant as previous test a week ago gave a faint positive or could the pesseries just be delaying my period please help

    1. Hi there, I had a similar situation. I took a test on the 7th day after my 5 day blastocyst transfer and it showed negative but with an ever so very faint positive line. I took it again on the 14th day as I was told by my clinic and it showed up positive.

      I think it’s best to consult your fertility clinic for advice and a blood test to confirm. I have to go later this week to do that. I know it’s super stressful to not know or be certain but they are the professionals and should be providing you with the right advice and care:). Goodluck and I am sending positive vibes over

  40. I took a test 9 days after 5 day transfer the test was negative but I am 7 days late on my period is there any chance I could still be pregnant as previous test a week ago gave a faint positive or could the pesseries just be delaying my period please help

    1. Hi there, I had a similar situation. I took a test on the 7th day after my 5 day blastocyst transfer and it showed negative but with an ever so very faint positive line. I took it again on the 14th day as I was told by my clinic and it showed up positive.

      I think it’s best to consult your fertility clinic for advice and a blood test to confirm. I have to go later this week to do that. I know it’s super stressful to not know or be certain but they are the professionals and should be providing you with the right advice and care:). Goodluck and I am sending positive vibes over

  41. I got positive result after embryo transfer I’m using vaginal progestron tablets so how long I should use progestron tablets

  42. I got positive result after embryo transfer I’m using vaginal progestron tablets so how long I should use progestron tablets

  43. Hi all, I was unable to refill my progesterone capsules over New Years Eve and Day (as everywhere was closed), so I was told to supplement with an extra shot of the oil (I was already taking 1 1mL injection daily, so took 1 extra shot each day). I am back on the capsule + injection regimen, but I’m worried I have jeopardized the pregnancy. Has anyone been thru something similar or know if this short term supplementation can work out ok?

  44. Hi all, I was unable to refill my progesterone capsules over New Years Eve and Day (as everywhere was closed), so I was told to supplement with an extra shot of the oil (I was already taking 1 1mL injection daily, so took 1 extra shot each day). I am back on the capsule injection regimen, but I’m worried I have jeopardized the pregnancy. Has anyone been thru something similar or know if this short term supplementation can work out ok?

  45. Hello I had frozen embryo transfer yesterday I fogot to take progestin injection and I had suppository 13 hours later. Could i know the sequences of this missing…

  46. Hello I had frozen embryo transfer yesterday I fogot to take progestin injection and I had suppository 13 hours later. Could i know the sequences of this missing…

  47. Hi I’ve just got a BFP from fresh ivf cycle at 10dp5dt my clinic had advised I don’t need to continue cyclogest pessaries now as my body will be producing progesterone at this stage. I know my clinic are the experts and I do trust what they advised but I’ve read a lot of clinics prefer patients to be on it anywhere up to 12 weeks pregnant so I am a little anxious, should I be concerned? Thank you x

  48. Hi I’ve just got a BFP from fresh ivf cycle at 10dp5dt my clinic had advised I don’t need to continue cyclogest pessaries now as my body will be producing progesterone at this stage. I know my clinic are the experts and I do trust what they advised but I’ve read a lot of clinics prefer patients to be on it anywhere up to 12 weeks pregnant so I am a little anxious, should I be concerned? Thank you x

  49. I would like know usually in ivf treatment until what gestation week, progesterone injections are recommended ? After how many weeks a lady could stop taking it ? Usually when placental take over progesterone production?

  50. I would like know usually in ivf treatment until what gestation week, progesterone injections are recommended ? After how many weeks a lady could stop taking it ? Usually when placental take over progesterone production?

  51. Hi I did my FET on Monday …have no symptoms of pregnancy yet.
    Really worried if it is success or not ?
    I need to take pregnancy test on 12th September.
    I am taking progestrone injections daily
    Please suggest

  52. Hi I did my FET on Monday …have no symptoms of pregnancy yet.
    Really worried if it is success or not ?
    I need to take pregnancy test on 12th September.
    I am taking progestrone injections daily
    Please suggest

  53. Hi , im after frozen transfer. The doctor said to stop all medication- progesterone and estriadiol in 12 weeks of pregnancy. I had lower progesterone at 6 weeks and they increased to 800 mg . Should I stop all on this day? It is safe ? To stop them all ?

  54. Pls I have been taking cyclgest twice a day and traveling which will take abt 16 hrs to my destination. Would be a problem if I miss it during the flight since it will melt when I insert in the plane . It’s day 4 of my 5dt if yes can I replace it with progesterone in oil so I take that injection before my flight?

  55. I took injection into my buttock and more recently on second attempt for FET the pill. Although both give me headaches, the pill gave me horrible sharp stabbing migraines, vomiting all day, and so dizzy that I fell over and this lasted for several days for the 7 days I was taking it. I will never again use the pill form. I work and couldn’t even drive or function.

  56. You don’t have to lie down for 30 minutes after using Crinone. It’s actually better to get up and walk around so that it gets coated fully and therefore absorbs better

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