Prednisolone has been contentious in the fertility world for years. Some clinics prescribe it after repeated embryo transfer failure or miscarriages. It’s effectiveness as immunological treatment in fertility cycles is far from clear.
Does Prednisolone help woth pregnancy? For most IVF patients, the evidence says no. But that doesn’t mean it should be excluded as an option… for certain patients.
Prednisolone can certainly help with medical conditions like asthma, arthritis, inflammatory bowel disease and some allergic reactions. But as a routine add-on for every fertility patient? No. Studies show little benefit. The risks of taking it are also overlooked.
What is Prednisolone?
Prednisolone is a corticosteroid. It has anti-inflammatory qualities and can suppress parts of the immune system by mirroring cortisol, a hormone made by the adrenal glands.
Prednisone is closely related to Prednisolone. Both work in similar ways, but Prednisone is metabolised in the liver. When patients are prescribed steroids by our Czech clinic, they take Prednisone. The liver can handle it well in most cases.
Using Prednisolone for a recognised medical condition isn’t the same as adding it to an IVF protocol. It needs to be considered very carefully by fertility clinics. Some studies suggest a possible benefit for recurrently unsuccessful IVF patients. The majority, however, don’t.
Why is Prednisolone used in IVF?
Prednisolone is sometimes used in fertility treatment to guard against immune activity that may negatively affect implantation. It tends to be offered to patients with:
- Recurrent implantation failure
- Recurrent miscarriage
- Elevated natural killer cell scores
- Previous unsuccessful IVF cycles
The general theory is persuasive: reduce inflammation, dampen down immune activity, make the uterus more receptive. But, as discussed, strong evidence for its use in fertility cycles is thin on the ground.
Let’s look more closely. The biological action of Prednisolone isn’t proof it leads to better outcomes after a fertility cycle. Suppressing your immune system arbitrarily just may not help. It could even disrupt certain processes in your body and have a detrimental effect on your chances of success.
Can natural killer cells attack an embryo – and can Prednisolone help?
Despite the alarming name, natural killer cells don’t simply attack an embryo. NK cells are hotly debated by IVF patients on forums. Who would ignore such a dramatic name, and who wouldn’t want to protect their embryos from this immune mischief?
There’s no mischief. Protection doesn’t seem to be needed by the use of Prednisolone. Uterine (uNK) natural killer cells are normal and help with placental development in early pregnancy. They’re different to NK cells in the blood. A blood result can’t show what NK activity is happening in the uterine lining.
And yet, for years, blood NK results were the yardstick for fertility clinics prescribing immunology-based medication like Prednisolone. These days, an assessment of the endometrium is a better way to start looking at immunology factors. But even then, cells as implantation killers? Many doctors don’t buy it.
There’s no accepted definition of what an abnormally high uterine NK-cell level is. Nor what the threshold is before using Prednisolone to improve outcomes. A clinic’s approach is more nuanced. The relevant question is: might this particular patient benefit? Here’s a fertility doctor’s view on Prednisone.
The HFEA isn’t convinced that immune cells cause pregnancy failure either. Safety concerns and insufficient evidence, it says, make the case for avoiding Prednisolone in most fertility protocols. But most doesn’t mean all. Read on to see if the steroid might help certain patients, including you.
What’s the latest research on Prednisolone and fertility treatment?
Earlier Prednisolone studies were small. Some looked at the combined effect of steroids and low dose aspirin and/or Clexane, Even when some outcomes were promising, researchers couldn’t be sure if Prednisolone had a real benefit.
A trial from 2023 looked at Prednisone and IVF. Patients with recurrent implantation failure (each had at least two failed embryo transfers) were given either 10 mg of Prednisone daily, or a placebo. The result? Prednisone didn’t improve live birth rates.
More worryingly, the trial found signs of potential harm. Premature births happened in 11.8 per cent of pregnancies in the Prednisone group. The placebo group figure was 5.5 per cent. Biochemical pregnancies appeared to be more frequent after taking Prednisone.
The caveats? It was a small trial – 715 women took part. And 10 mg daily is quite a high dose (our clinic usually recommends 5 mg). The researchers cautioned against routine use. So, as mentioned, Prednisolone in fertility treatment is a bespoke, not a routine option. Responsible clinics should prescribe it on a case-by-case basis.
NICE’s review into fertility immunology add-ons reached a similar conclusion. It found no good evidence that steroids boosted live birth rates or reduced miscarriages. It took a decidedly cautious against to immune therapies in the fertility context.
Then a killer blow. A systematic 2026 review of common IVF add-ons found little compelling evidence for most add-ons, including steroids like Prednisolone. It was, is some ways, a devastating dismantling of fertility extras. Even PGT-A testing was dismissed. And even a cheap and popular one, embryo glue, got short shrift.
Does Prednisolone prevent recurrent miscarriage?
There’s no substantive evidence that Prednisolone, routinely taken, prevents unexplained miscarriage. Miscarriages mainly happen due to chromosomal anomalies in the embryo. Or because of uterine issues or certain haematological conditions. Suppressing your immune system doesn’t fix these.
So, what should you do if you’re a fertility patient with a history of failed treatments? Ask your clinic for a proper reassessment. Ask if immune medications, such as Prednisolone or intralipid infusions, could be considered in your next treatment.
Your clinic may prioritise a uterine-cavity assessment like a hysteroscopy first. Or antiphospholipid syndrome testing. Or further hormone checks, like a TSH test. Or even karyotype tests for you and your partner. The immune side of things often takes a back seat. At least initially.
When is Prednisolone a good idea in fertility treatment?
Prednisolone can help, as discussed, with certain autoimmune, inflammatory or respiratory diseases. But can it help the occasional fertility patient?
There are two main questions.
First, if a fertility patient has any of the above conditions, should Prednisolone be taken during her treatment? Care should be taken, and conversations had, between the fertility clinic and the doctor managing the underlying condition.
Second, are known or suspected autoimmune disorders the one area to focus on? Seeing a reproductive immunologist may help. The body’s immune system is a finely balanced instrument. An immunologist could see something, usually in a blood result, that may require a steroid like Prednisolone, or another immunological treatment.
The performance of the lectin pathway, within the immune system, is one area immunologists look at when there’s a pattern of recurrent miscarriage or pregnancy loss. Reproductive immunology is a new science. Practitioners are hard to find, and often expensive. Ask your clinic for the best approach here.
Prednisolone dosage during IVF
There’s no standard dose of Prednisolone in fertility cycles. However, many clinics stick to a low daily dose of 5 mg. For certain patents, 10 mg to 20 mg daily is used, often tapered. Dosages rarely exceed this.
Prednisolone is often started before embryo transfer or on transfer day itself. After a positive pregnancy test, you’ll probably be asked to take it until the rest of your fertility medication is stopped, later in the first trimester.
Prednisolone side effects
A low-dose course for a few weeks shouldn’t cause any significant problems. Possible side effects for fertility patients include:
- Insomnia and restlessness
- Anxiety, irritability or mood changes
- Indigestion or abdominal discomfort
- Fluid retention and higher blood pressure
- Increased blood glucose
- Greater susceptibility to infection
Risks generally increase when the dose is higher or its usage longer, We know that sustained use of Prednisolone can affect muscles, bones and adrenal function. So it’s not a multivitamin. These small, inexpensive pills pack a punch.
Do you need to taper Prednisolone?
Some steroids need to be reduced gradually, allowing a phased takeover by the adrenal glands for cortisol production, Tapering off Prednisolone over one or two weeks is quite common for fertility patients. Weaning off IVF medication correctly is important.
Prednisone and fertility – in summary
Prednisolone is an established medication in general medication. But that doesn’t make it a fertility wonder drug.
For medically healthy IVF patients, current evidence shows no improvement in live birth rates, with recurrent implantation failure or not. Fertility experts say the benefit of routine steroid use for these patients is unproven.
So be cautious. If you see Prednisolone on your protocol, ask your clinic the reason why and request evidence for its inclusion. Your immune system usually works with you, not against you. Your clinic needs to explain why you need it.
Your questions answered
Prednisolone doesn’t improve live birth rates in otherwise healthy IVF patients. A large placebo-controlled trial looking at its use in patients with recurrent implantation issues found no benefit. Prednisolone may still be needed for diagnosed inflammatory or autoimmune conditions.
Clinics may prescribe it to suppress immune or inflammatory activity around implantation. It’s sometimes offered after a number of failed embryo transfers, miscarriages, or when abnormal immunology results are seen. However, clinic approaches vary.
Current evidence doesn’t prove that Prednisolone boosts implantation or live birth rates. Some older, smaller studies saw encouraging pregnancy outcomes, but many had limitations or looked at combining steroids with other drugs. So, Prednisolone’s individual effect on fertility cycles was hard to determine.
Routine Prednisolone use hasn’t been shown to prevent miscarriage after IVF. Steroids may be prescribed for a genuine maternal medical condition, but that’s different to using them as miscarriage prevention.
There’s no clear ‘high-NK-cell’ threshold that predicts IVF failure or shows who will benefit from steroids. Blood and uterine NK cells are also not the same. Many fertility bodies don’t recommend NK-cell testing – of blood or uterine cells – or the routine use of Prednisolone to guard against NK-cell activity.
Fertility protocols vary, with some clinics prescribing 5 mg or 10 mg daily and others using different doses. There’s no universally accepted approach. Only take the dose prescribed for you, and request written instructions covering timing, monitoring and tapering.
It’s often started shortly before transfer, or on transfer day itself. Then it’s stopped after a negative test or continued into early pregnancy. Because no standard approach exists, follow your clinic’s instructions and clarify the plan before starting and stopping them.
Don’t stop without first speaking to your clinic. Some protocols allow you to end Prednisolone abruptly, while others require a more gradual tapering. It depends on dose, duration and your situation. Ask your clinic for a written schedule and stick to it.
Side effects can include insomnia, restlessness, anxiety, irritability, and indigestion. Steroids suppress immunity, increasing your susceptibility to infection and other issues. Larger doses and prolonged treatment generally mean greater risks. Most fertility patients take low doses of Prednisolone for a relatively short period – so the risks are lower.
Ask why your doctor or clinic recommends it, and if good-quality evidence supports its use on your case. Check if it might improve your chances of a successful live birth, and what the alternatives are. Ensure you understand the precise dose and duration, and how to wean off the Prednisolone.
66 Responses
Hello , i just wondering this is right that doctor after IVF tell me to take 2 time a day prenisolone and how this tablets can effect my pregnacy ?
Hi Ren, just wondering how are you doing with your IVF? I’m waiting for my BETA result today (blood withdrawn yesterday), and for the past 14 days been taking Prednisone twice a day. IVF 5th day blastocyst FET. Thanks.
Hello , i just wondering this is right that doctor after IVF tell me to take 2 time a day prenisolone and how this tablets can effect my pregnacy ?
Hi Ren, just wondering how are you doing with your IVF? I’m waiting for my BETA result today (blood withdrawn yesterday), and for the past 14 days been taking Prednisone twice a day. IVF 5th day blastocyst FET. Thanks.
I’ve been prescribed this drug twice along with clomiphene citrate. I got a month’s worth of the prednisone but I didn’t finish them (stopped last friday). I was not made aware by my gynecologist that this was a steroid nor the side effects until I researched. I plan on going to another as there has to be a better and safer option.
I’ve been prescribed this drug twice along with clomiphene citrate. I got a month’s worth of the prednisone but I didn’t finish them (stopped last friday). I was not made aware by my gynecologist that this was a steroid nor the side effects until I researched. I plan on going to another as there has to be a better and safer option.
I am currently taking prednisone 20mg tablets. Is this safe? Per tour article, it states “no more than 20mg”. I have been married 16yrs, and we have been trying for 14yrs to conceive, been on numerous cycles of Clomid, had a couple of Hysterosalpingogram done, had my uterus and ovaries checked with ultrasound, every test an procedure I have done have all come back normal. Only explanation I have been given, unexplainable, but see nothing wrong for us to conceive. Last year we visited with a fertility specialist, and we will need to come up with about $750 to begin fertility treatment. In conclusion, can I continue with taking and finishing the prednisone that I am on, and engage in intercourse with my husband? This week I should be ovulating, according to the period diary app I use.
I am currently taking prednisone 20mg tablets. Is this safe? Per tour article, it states “no more than 20mg”. I have been married 16yrs, and we have been trying for 14yrs to conceive, been on numerous cycles of Clomid, had a couple of Hysterosalpingogram done, had my uterus and ovaries checked with ultrasound, every test an procedure I have done have all come back normal. Only explanation I have been given, unexplainable, but see nothing wrong for us to conceive. Last year we visited with a fertility specialist, and we will need to come up with about $750 to begin fertility treatment. In conclusion, can I continue with taking and finishing the prednisone that I am on, and engage in intercourse with my husband? This week I should be ovulating, according to the period diary app I use.
I have been trying to conceive for 10 years now, I have pcos, I have never received any fertility treatment, nor have I ever been pregnant, that was until December 2016 when I fell pregnant whilst taking prednisone, sadly that pregnancy ended in miscarriage at 8 weeks. I was only in Prednisone for 10 days for a chest infection so I never expected it would help me get pregnant. I have told my doctor that when I got pregnant I was on prednisone but they refuse to prescribe it me and they are well aware of my struggle to get pregnant. I have not been able to get pregnant since, no offer of help or any interest from Doctors of my fertility. If ever there comes up any trials to help women get pregnant on prednisone then I would happily put myself forward for it. I am saving up for surrogacy but if I can get pregnant naturally by taking prednisone then I would happily go for
It
I’m confused by your comment. You said you’ve never had fertility treatment. Wouldn’t that be the first step, rather than jumping to surrogacy???
Hi pagan,
M Dr Devendra from India.
I m a gynecologist ..I want to tell u one thing if u have got pregnant once half d battle u have won…it means there is nothing wrong in d process of fertilization and implantation ..only thing is, u have to continue it till term…which includes lot of things like ur age, normal uterine structure, hormonal level in body, h/o any infection and nutrition…once all dis factors work well der shudnt b a problem to make it reach till term….wish u a good luck.
This is very comforting news for me, doctor, because I have a two-year-old daughter and we have been trying to have another child for a year now. my daughter still eats breasts sometimes at night, I don’t know if it still affects my fertility because my cycles are regular, but I haven’t been pregnant for a year and I was wondering if everything was OK with me… now I hope it’s just a matter of time… what tests does the doctor suggest?
Don’t take no for an answer. If your FS refuses to prescribe it, tell them you’re going to look for an FS who will. Your family doctor could also prescribe it,
These doctors just don’t get it, a lot of the time we know what’s best for our bodies.
You have to be courageous and be bold 🙂
Trust your instincts and read loads of success stories from reading various fertility forums.
The use of prednisone and baby aspirin and Lovenox has been a game changer for so many women with failed attempts including myself. There’s no real harm & if it works great 🙂
Hi Jen, I just read your comment. Did you use all 3 prior to pregnancy – aspirin, prednisone and clovox? Did your gynecologist prescribed them? With prednisone do your remember how long you had to take it for? I had 2 miscarriages and I failed transferred (didn’t get a positive pregnancy result).
My Fertility doc has put me on it after egg retrieval. If you go to a fertility doctor they will prescribe it. So far I’m supposed to be on it until I do my pregnancy test in a week after transfer. You can also request it for other reasons like skin conditions and allergies. Then just try to get pregnant. Supposedly it’s taken up to week 12 only. They also have me on progesterone pills (5 /day) and some other estrogen to support the uteraean lining. Also if you’re Rh – and your partner if Rh positive it’s common for your body to attack the Cetus and kill it and miscarry. You can get the rho gham injection so you won’t kill his Sperm or the Cetus and this prevents rh miscarriage. Don’t give up! Also seeing a naturopath that specializes in Fertility will help. The longer you wait the less likely you’ll get pregnant so explore a fertility clinic now or freeze some eggs. Good luck dear 🙂
Hi Ashley,
Do you mind me asking at how many weeks they gave you RhoGham injection?
For Rh – and your partner if Rh +
I have been trying to conceive for 10 years now, I have pcos, I have never received any fertility treatment, nor have I ever been pregnant, that was until December 2016 when I fell pregnant whilst taking prednisone, sadly that pregnancy ended in miscarriage at 8 weeks. I was only in Prednisone for 10 days for a chest infection so I never expected it would help me get pregnant. I have told my doctor that when I got pregnant I was on prednisone but they refuse to prescribe it me and they are well aware of my struggle to get pregnant. I have not been able to get pregnant since, no offer of help or any interest from Doctors of my fertility. If ever there comes up any trials to help women get pregnant on prednisone then I would happily put myself forward for it. I am saving up for surrogacy but if I can get pregnant naturally by taking prednisone then I would happily go for
It
I’m confused by your comment. You said you’ve never had fertility treatment. Wouldn’t that be the first step, rather than jumping to surrogacy???
Hi pagan,
M Dr Devendra from India.
I m a gynecologist ..I want to tell u one thing if u have got pregnant once half d battle u have won…it means there is nothing wrong in d process of fertilization and implantation ..only thing is, u have to continue it till term…which includes lot of things like ur age, normal uterine structure, hormonal level in body, h/o any infection and nutrition…once all dis factors work well der shudnt b a problem to make it reach till term….wish u a good luck.
Don’t take no for an answer. If your FS refuses to prescribe it, tell them you’re going to look for an FS who will. Your family doctor could also prescribe it,
These doctors just don’t get it, a lot of the time we know what’s best for our bodies.
You have to be courageous and be bold 🙂
Trust your instincts and read loads of success stories from reading various fertility forums.
The use of prednisone and baby aspirin and Lovenox has been a game changer for so many women with failed attempts including myself. There’s no real harm & if it works great 🙂
My Fertility doc has put me on it after egg retrieval. If you go to a fertility doctor they will prescribe it. So far I’m supposed to be on it until I do my pregnancy test in a week after transfer. You can also request it for other reasons like skin conditions and allergies. Then just try to get pregnant. Supposedly it’s taken up to week 12 only. They also have me on progesterone pills (5 /day) and some other estrogen to support the uteraean lining. Also if you’re Rh – and your partner if Rh positive it’s common for your body to attack the Cetus and kill it and miscarry. You can get the rho gham injection so you won’t kill his Sperm or the Cetus and this prevents rh miscarriage. Don’t give up! Also seeing a naturopath that specializes in Fertility will help. The longer you wait the less likely you’ll get pregnant so explore a fertility clinic now or freeze some eggs. Good luck dear 🙂
Hi just finished my second try of IVF blastocyst, was unsuccessful, can’t understand why cos my first try I fell pregnant but had miscarriage, didn’t know about Prednisone and wondering how new is this therapy as my doctor never suggested it. Wondering if I should go for another cycle!
Hi just finished my second try of IVF blastocyst, was unsuccessful, can’t understand why cos my first try I fell pregnant but had miscarriage, didn’t know about Prednisone and wondering how new is this therapy as my doctor never suggested it. Wondering if I should go for another cycle!
It mentions that it may affect foetal growth…in what way?
It seems to leave more questions that it answers.
Can anyone help me with this please?
It mentions that it may affect foetal growth…in what way?
It seems to leave more questions that it answers.
Can anyone help me with this please?
To the ladies above who are on the steroid, what dose are you on each day?
Cheers
To the ladies above who are on the steroid, what dose are you on each day?
Cheers
2nd round of ivf. This time prescribed predisinfection, aspirin, estrofem and progesterone but not folic acid. Just wondering whether it is still OK to take the pregnacare vitamin and folic acid supplements?
2nd round of ivf. This time prescribed predisinfection, aspirin, estrofem and progesterone but not folic acid. Just wondering whether it is still OK to take the pregnacare vitamin and folic acid supplements?
I am on my way to Greece to have a donar egg implanted. I am on Prednisolone as well has having intralipid infusions. This is my 5 time so am hoping is all works this time
Hi Christine. I was just wondering if you were successful and why you chose Greece. I am Greek by the way!
I am on my way to Greece to have a donar egg implanted. I am on Prednisolone as well has having intralipid infusions. This is my 5 time so am hoping is all works this time
Hi Christine. I was just wondering if you were successful and why you chose Greece. I am Greek by the way!
30 years ago I went to an Endocrinologist who specialized in Infertility. He looked at my ovulation temperature charts, and put me on Prednisolone 2.5mg a day and I became pregnant within 3 months. Three years later I went back on same dose and got pregnant the first month.
do you mind me asking how long you stayed on it and if your dose changed? thanks
30 years ago I went to an Endocrinologist who specialized in Infertility. He looked at my ovulation temperature charts, and put me on Prednisolone 2.5mg a day and I became pregnant within 3 months. Three years later I went back on same dose and got pregnant the first month.
do you mind me asking how long you stayed on it and if your dose changed? thanks
Hi…can u tell me for how long u took prednisolone?
Amazing
How long where you on it
Hello.
I’m actually in 10 week pregnancy and 8 week after I conceive and currently taking 20 mg predninsolone.I know that I should take two weeks more but after that should decrease 5 Mg per day said my doctor.It’s it ok?He don’t told me that I should decrease all the pills
Hi did you take it before getting pregnant alextwin?
I’m currently on it for high amount of killer cells which are stoping me from getting pregnant they gave me to help reduce and hopefully I can carry .
Thanks
Hello.
I’m actually in 10 week pregnancy and 8 week after I conceive and currently taking 20 mg predninsolone.I know that I should take two weeks more but after that should decrease 5 Mg per day said my doctor.It’s it ok?He don’t told me that I should decrease all the pills
Hi did you take it before getting pregnant alextwin?
I’m currently on it for high amount of killer cells which are stoping me from getting pregnant they gave me to help reduce and hopefully I can carry .
Thanks
after 10 days of 5th day embryo blastocyst done , results are positive in beta hcg.
my wife got rashes on skin ,side effect of medicine and started attecking to respiritri system so my doctor suggested for steroids and said that it may harm to pregancy. she is been pregnant after 8 years .
Will it harm to my wifes pregnancy.
after 10 days of 5th day embryo blastocyst done , results are positive in beta hcg.
my wife got rashes on skin ,side effect of medicine and started attecking to respiritri system so my doctor suggested for steroids and said that it may harm to pregancy. she is been pregnant after 8 years .
Will it harm to my wifes pregnancy.
Hi
I conceived in 3rd ivf cycle. Now I’m in my 3rd week. Previously I had couple of blighted ovums, ruptured ectopic pregnancy and underwent many procedures but with no gain for 7 yrs. In this cycle, My fertility doc prescribed me wysolone 10mg from the day of egg retrieval after finding my HBA1c levels normal along with progesterone, estrogen & heparin. I’m worried if this 3 week duration of steroid intake wud have caused any fetal anomaly?? Plz can any 1 help me out with my confusion.
Hi
I conceived in 3rd ivf cycle. Now I’m in my 3rd week. Previously I had couple of blighted ovums, ruptured ectopic pregnancy and underwent many procedures but with no gain for 7 yrs. In this cycle, My fertility doc prescribed me wysolone 10mg from the day of egg retrieval after finding my HBA1c levels normal along with progesterone, estrogen & heparin. I’m worried if this 3 week duration of steroid intake wud have caused any fetal anomaly?? Plz can any 1 help me out with my confusion.
Hi sir four months ago I had a skin disease and the doctor placed me on Prednisolone for one week but I am still on it till date will it affect my bearing children
Hi sir four months ago I had a skin disease and the doctor placed me on Prednisolone for one week but I am still on it till date will it affect my bearing children
I am roughly 4 weeks prenant and my doc just did a vaginal ultrasound confirming we are having 2 babies.. However, while viewing the ultrasound she found a quite a bit of liquid away from the embryos and prescribed baby aspirin and meticorten 5mg… I googled this medicine and it says something about fetal development, basically negative comments. I just dont know if I should take it or not… Is it safe?
I am roughly 4 weeks prenant and my doc just did a vaginal ultrasound confirming we are having 2 babies.. However, while viewing the ultrasound she found a quite a bit of liquid away from the embryos and prescribed baby aspirin and meticorten 5mg… I googled this medicine and it says something about fetal development, basically negative comments. I just dont know if I should take it or not… Is it safe?
Hi. I am currently 5 weeks and got prescribed the same. Can you tell me if it was beneficial for you? I’ve struggled and have had a couple of miscarriages, so I really appreciate it if you can tell me your experience. I don’t want anything to harm my baby.
Hi have been taking predinisone for the last 8 years for chest infections .can it causes infertility. Have been trying to concieve but no result of pregnancy
Hi have been taking predinisone for the last 8 years for chest infections .can it causes infertility. Have been trying to concieve but no result of pregnancy
hi im about to go into my fourth cycle of Ivf this time round being treated for an immune problem so I’m being put on 10mg prednisone as well as clexane a blood thinner also I’ll be having lubion injections as well as the pessaries I’m praying I have my miracle this time round does anyone know if I’ll gain a lot of weight on 10mg of predisone and has anyone else got any succes from using these drugs please?
So what is the main work of prednisolone in early pregnancy or side effects?
I have my third donor egg transfer. I’ve been prescribed steroids for potential inflammation due to a mild insulin resistance, for which I will take metformin. I do not have diabetes yet thankfully. I’ve been prescribed Dexamethasone 1,5mg/day until embryo transfer. After embryo transfer, I should take Prednisone 10mg.
I don’t know whether or not to take these steroids as I am worried about the potential side effects. Has anyone had any positive or negative experience of these and/or any advice as one day I think I should just take them as they’ve been recommended by a doctor and the next day I’m just scared that I’m being asked to take something that may cause harm with no guarantees. Any guidance greatly appreciated and wishing you health, luck and happiness for the new year.
Hi Angelina, I’ve had 2 successful pregnancies on 10mg prednisone (solupred)/baby aspirin/uterogestan 200mg and lovenox injections daily for 14 weeks. My two babies were born healthy. Before them, I had eight miscarriages and I am thankful to God that this combo worked well for me. I hope and prays it works out for you too.
Maryan…. did you stop your prednsoln treatment @ 14 weeks?
I’m currently 13 weeks, 10 mg prednisoln and I’m getting conflicting information from my doctors- did you taper off. I feel so lost in this- Any information would be great.
Thank you Maryan for replying. I almost forgot that I’d posted this message and was googling steroids again generally and I came across your reply by chance. I will now see this as a sign! It’s great to hear that it worked for you and that your little ones are healthy. I’m not sure if you’ll see this message as it’s been some months since your message but do you recall how you felt on the steroids? Did they affect your health at all? Thank you so much for taking the time to share your experience to help me. Best wishes.
Hi all, was trying to get pregnant for ten years, doctor prescribed me 5mg Prednisone for a chest infection (didn’t know this helped fertility)! Was on them for 5 days only and fell pregnant! I am now 10weeks 4days, over the moon! Id recommend these to anyone trying. It worked for me, never tried IVF due to financial difficulty was in the frame of mind if I happens it happens if not then not meant to be! I wish I’d known about this sooner! Go for it girl what do you have to lose?! X
Greetings- I’ll open this up for comment if anyone is out there.
PREDiSOLN Therapy, when and how to stop? (currently 13 weeks) ANXA5 MR2 positive.
My original doctor who prescribed prednisoln is now unavailable – horrible timing and my current OB has not a clue and just wants me off everything- not wise. Scrambling for an informed OBGYN and looking for a consult w an experienced w high risk pregnancies -NO luck- the clock is ticking.
After 7 years of infertility and RPL many many an early miscarraige- I am finally pregnant with my one and only successful egg after many retrieval’s. ANXA5/ MR2 causes a whole host of placental complications, clotting issues- pre- eclampsia etc.
I’m doing the standard protocol of Low Molecular Heparin (neoparin/celexane) low does aspirin and 10mg prednisone which my new OBGYN refuses to refill- not cool.
Most of what I’m reading suggests tapering off the prednisoln at 12- 14 weeks—- anyone have suggestions or know of a really informed OBGYN I can get a phone consult with. ??
Infact am happy for all ur experience, I have been looking for pregnancy for 15yrs now, and have miscarriage up to 8 times b4 and after my last baby,no money for ivf, pls I need ur help and advice for what to do next.
Hello, I am in the middle of a IVF process pro transfer days prior to the transfer. My progesterone, hormones, level was low, but then I was take you prednsion 10 mg with aspirin for four days three times a day with estradiol could that raise my pedestrion hormones level? Please respond asap.. thank you
Hello, I took prednisolone at 7-8 weeks of pregnancy at 20 mg per day for 8 days. How will it affect the fetus? is it dangerous